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Tri-Hist Granules

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Tri-Hist® Granules
Product Information
Tri-Hist® Granules are an antihistamine and decongestant combination used to relieve or prevent the symptoms of allergies. 
Generic Name
Pyrilamine, Pseudoephedrine
Brand Names
Tri-Hist® Granules
Drug Class
Antihistamine, Decongestant
Neogen Corporation
Product Description & Form
Tri-Hist® Granules 567 gm Tub: yellow granules. (NDC 59051-8874-06)
  • Helps alleviate skin and respiratory allergies such as congestion, hives (urticaria), runny nose, and itching
  • Highly palatable cornmeal base
  • Container comes with 1 scoop equal to 1/2 ounce
  • Each ounce contains 600 mg pyrilamine and 600 mg pseudoephedrine
Active Ingredients
Pyrilamine maleate, Pseudoephedrine hydrochloride 
Tri-Hist® Granules should be given to your horse as directed by your veterinarian. May be easily administered by mixing with feed, and provide horse with ample drinking water.
Missed Doses
Give the dose as soon as possible. If it is almost time for the next dose, skip the missed dose, and continue with the regular schedule. Do not give 2 doses at once.
Side Effects
Side effects may include upset stomach, diarrhea, dizziness, drowsiness, nervousness, insomnia tremors, difficulty walking, muscle weakness, rapid heart rate, and increased blood pressure. Notify your veterinarian if these effects are troublesome and continue.
Other side effects may occur. If you notice anything unusual, contact your veterinarian.
Drug & Food Interactions
The following drugs can potentially interact with Tri-Hist®: epinephrine, heparin, phenylpropanolamine, reserpine, MAO inhibitors, warfarin and CNS depressants. Contact your veterinarian if your horse experiences any unusual reactions when different medications are given together.
Make sure to tell your veterinarian what other medication you are giving to your horse. Quite often your veterinarian may prescribe two different medications, and a drug interaction may be anticipated. In this case, your veterinarian may vary the dose and/or monitor your horse more closely. 
Allergic reactions to medications may occur. Be sure to inform Vetsource and your veterinarian if your horse has any known drug sensitivities or allergies. If your horse displays symptoms of an allergic reaction, call your veterinarian immediately or go to a veterinary emergency clinic. Symptoms may include but are not limited to: swollen lips, tongue, face, airways; difficulty breathing; agitation; profuse salivation; widespread hives and itching.
Adverse Reactions
If you are concerned that your pet has experienced an adverse reaction to this medication, please contact the manufacturer Neogen at 800-525-2022 or Vetsource customer service at 877-738-4443.
Store at 59°F to 86°F in controlled room temperature. Keep this medicine out of reach of children. Store in a childproof container. Store this medicine in a cool, dry place at room temperature. Store away from heat and direct sunlight. Do not store this medicine in the bathroom, near the kitchen sink or in damp places. The medicine may break down if exposed to heat or moisture.
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Nutritional Info