Phenylbutazone Boluses

Phenylbutazone Boluses

Phenylbutazone is a synthetic non-steroidal anti-inflammatory medication used primarily for the treatment of musculoskeletal pain and inflammation in horses. It may also be used in some cases to lower fever, or to treat osteoarthritis and rheumatism in other animals. Each tablet/bolus contains 1 gram of phenylbutazone.

Horses

Phenylbutazone

Pributazone®; Equi-Bute EQ® (paste); Equizone™ (powder); Phenylbute® (powder, injection)

Non-Steroidal Anti-inflammatory Drug (NSAID)

Phenylbutazone 1 gm Boluses: 18mm, round, white tablet/bolus, scored in half, imprinted with BUTE/1 GM. (Manufacturer: Priority Care; NDC: 58829-0334-10)

Phenylbutazone

Phenylbutazone Boluses should be administered to your horse as directed by your veterinarian.

For oral use in horses only.

Orally - 1 to 2 boluses per 500 lb. body weight. Do not exceed 4 grams daily. Reduce dosage as symptoms regress. Intermittent treatment given only when symptoms appear may be indicated.

Administer the dose as soon as possible. If it is almost time for the next dose, skip the missed dose and continue with the regular schedule. Do not give two doses at once.

Reported side effects in horses may include (but are not limited to) oral and GI erosion/ulcers, diarrhea, decreased appetite, kidney damage, & colitis. If these or other troublesome symptoms appear, discontinue and contact your veterinarian.

Dogs may experience sodium & water retention and decreased renal blood flow.

Contact your veterinarian immediately if the following symptoms are noted: changes in appetite, changes in drinking habits and urination frequency, seizures, coma, hyperventilation, persistent nausea and/or diarrhea, severe hypotension, depression, and weakness.

Other side effects may occur. If you notice anything unusual, contact your veterinarian.

The following medications have been noted to have potential interactions with phenylbutazone (but may not be a comprehensive list): angiotensin-converting-enzyme (ACE) inhibitors, corticosteroids, digoxin, furosemide (and other loop diuretics), hepatotoxic drugs, methotrexate, misoprostol, NSAIDs, phenobarbital, potassium-sparing diuretics, sulfonamides, tricyclic antidepressants, selective serotonin reuptake inhibitor (SSRIs), warfarin, and zonisamide.

Contact your veterinarian if your pet experiences any unusual reactions when different medications are given together.

Ensure your veterinarian is aware of all medications and/or supplements you are giving to your pet. Quite often your veterinarian may prescribe two different medications, even if a potential drug interaction may occur. In this case, your veterinarian may vary the dose and/or monitor your pet more closely.

For oral use in horses only. Not for use in humans.

Avoid or use with caution in patients with history of hypersensitivity or allergy to phenylbutazone.

Concomitant use with other anti-inflammatory drugs, such as NSAIDS or corticosteroids, should be avoided or closely monitored. In the treatment of inflammatory conditions associated with infections, specific anti-infective therapy should be used concurrently.

Do not use in horses intended for human consumption.

Federal law prohibits the extra-label use of this product in female dairy cattle 20 months of age or older.

Allergic reactions to medications may occur. Be sure to inform Vetsource and your veterinarian if your pet has any known drug sensitivities or allergies.

If your pet displays symptoms of an allergic reaction, discontinue therapy and call your veterinarian immediately or go to a veterinary emergency clinic. Symptoms may include (but are not limited to): swollen lips/tongue/face/airways, difficulty breathing, agitation, profuse salivation, and widespread hives/itching.

If you are concerned that your pet has experienced an adverse reaction to this medication, please contact the manufacturer Priority Care (First Priority, Inc) at 800-650-4899 or Vetsource customer service at 877-738-4443.

Store in a cool, dry place at controlled room temperature (59°F to 86°F). Keep the medication tightly closed in the original container and out of the reach of children and other animals. Store away from heat and direct sunlight. Do not store this medication in the bathroom, near the kitchen sink, or in damp places. The medicine may break down if exposed to heat or moisture.