PromAce (Acepromazine) Injection

PromAce® Injection

PromAce® Injection is used as a sedative and a pre-anesthetic agent.

Horses

Acepromazine

PromAce® 

Phenothiazine Sedative/Tranquilizer

Boehringer Ingelheim

PromAce® 10 mg/ml Injection 50 ml: yellow solution. (NDC 00010-3827-01)

Acepromazine maleate

Benzyl alcohol, trisodium citrate dihydrate, anhydrous citric acid, water.

PromAce® should be administered as directed by your veterinarian. Measure the dose with reasonable care.  Use aseptic techniques when withdrawing each dose to decrease the possibility of post-injection bacterial infections. Adequately clean and disinfect the stopper prior to entry with a sterile needle and syringe. Injectable medications require needles and syringes.  Those items are purchased separately.  Please ask your veterinarian for a recommendation for the correct needle/syringe sizes for your pet. Use only sterile needles/syringes and use each needle/syringe only once. Dispose the needle/syringe immediately in a proper sharps disposal container. Sharps containers are sold separately.

When used as labeled, there is no limit on the number of punctures throughout the full expiration date on the vial.

Give the dose as soon as possible. If it is almost time for the next dose, skip the missed dose, and continue with the regular schedule. Do not give 2 doses at once.

Side effects may include discolor in your horse’s urine to a pink or red-brown color. Your horse may become drowsy while taking this medication. Use with caution in stallions. May cause protrusion of the penis which could possibly lead to injury. Your horse’s blood pressure may decrease which may cause your horse to collapse. If this occurs, contact your veterinarian immediately.

Other side effects may occur. If you notice anything unusual, contact your veterinarian.

The following drugs can potentially interact with acepromazine: kaolin-pectin, bismuth subsalicylate compounds, antacids, propranolol, phenytoin, quinidine, epinephrine, other CNS depressants, atropine, barbiturates, barbiturate anesthetics, aminoglycoside antibiotics, phenylpropanolamine, tricyclic antidepressants (e.g. amitriptyline), and procaine. Contact your veterinarian if your pet experiences any unusual reactions when different medications are given together.

Make sure to tell your veterinarian what other medication you are giving to your pet. Quite often your veterinarian may prescribe two different medications, even if a drug interaction may occur. In this case, your veterinarian may vary the dose and/or monitor your pet more closely. 

Acepromazine should not be given to animals with strychnine or organophosphate poisoning or within one month of worming with an organophosphate agent. 

Allergic reactions to medications may occur. Be sure to inform Vetsource and your veterinarian if your horse has any known drug sensitivities or allergies. If your horse displays symptoms of an allergic reaction, call your veterinarian immediately or go to a veterinary emergency clinic. Symptoms may include but are not limited to: swollen lips, tongue, face, airways; difficulty breathing; agitation; profuse salivation; widespread hives and itching.

If you are concerned that your pet has experienced an adverse reaction to this medication, please contact the manufacturer Boehringer Ingelheim at 888-637-4251 or Vetsource customer service at 877-738-4443.

Store at 68°F to 77°F in controlled room temperature, excursions permitted between 59°F to 86°F. Keep this medicine out of reach of children. Store in a childproof container. Store this medicine in a cool, dry place at room temperature. Store away from heat and direct sunlight. Do not store this medicine in the bathroom, near the kitchen sink or in damp places. The medicine may break down if exposed to heat or moisture.